Our Research Projects

Research area: Hematopoiesis and Development


1.   Mechanobiology of the blood-bone marrow barrier and impact on platelet formation
     Supervisor:  Dr. Nathalie Brouard/Dr. Catherine Léon
     PhD Fellow: Faten Tlili
     Institution: University of Strasbourg (FR)

2.  Role of Ikaros in the development of Th17 lymphocytes
     Supervisor:  Dr. Susan Chan/Dr. Céline Charvet
     PhD Fellow: Caroline Targino
     Institution: University of Strasbourg (FR)

3.  Stroma – plasma cell interaction as driver of antibody-mediated autoimmune disease
     Supervisor: Prof. Dr. Reinhard Voll
     PhD Fellow: Paola Fernanda Ruiz Aparicio
     Institution: University Medical Center Freiburg (DE)

4.  Drug targeting of mesenchymal - hematopoietic cell interaction
     Supervisor: Dr. Christopher Mueller
     PhD Fellow: Guillermo Federico Perez
     Institution: University of Strasbourg (FR)

5.  3D model of olfactory mucosa immune defense against SARS-Cov2 infection
     Supervisor: Dr. Vincent Flacher
     PhD Fellow: Annia Pérez Riverón
     Institution: University of Srasbourg (FR)

6.  Investigating macrophage populations regarding cytomegalovirus infection
     Supervisor: Prof. Dr. Philipp Henneke
     PhD Fellow: Agnibesh Dey
     Institution: University Medical Center Freiburg (DE)

7.  Role of the Ikaros family proteins in embryonic blood cell development
     Supervisor: Dr. Susan Chan
     PhD Fellow: Mahassen El Khoury
     Institution: University of Strasbourg (FR)

 

Research area: Innate and Adaptive Effector Functions
 

8.  Regulation of the immune response by the spleen
     Supervisor: Dr. Blandine Maitre
     PhD Fellow: Gabriel Rojas Jiménez
     Institution: University of Strasbourg (FR) 

9.  Post translational modifications of IL-1β; regulation and roles in IL-1β activation
     Supervisor:  Prof. Dr. Georg Häcker
     PhD Fellow: Danielle Paige Anthony
     Institution: University Medical Center Freiburg (DE)

10. Modulating T cell signaling for improved anti-tumor responses
      Supervisor: Prof. Dr.  Björn Lillemeier
      PhD Fellow: Vasileios Morfos
      Institution: University of Freiburg (DE)

11.  Dysregulation of B cell function in ANCA associated vasculitis
      Supervisor:  Prof. Dr. Marta Rizzi
      PhD Fellow: Bruno Benassini
      Institution: University Medical Center Freiburg (DE)

12.  NLRP proteins in health and disease
      Supervisor: Prof. Dr. Olaf Groß
      PhD Fellow: Xipeng Wang
      Institution: University Medical Hospital Freiburg (DE)

13.  Monitoring affinity maturation during chronic viral infection
      Supervisor: Prof. Dr. Daniel Pinschewer
      PhD Fellow: Cemre Seven
      Institution: University of Basel (CH)

14.  Impact of macrophages signaling and metabolism on NLRP3 inflammasome activity
      Supervisor: Prof. Dr. Olaf Groß
      PhD Fellow: Clara Dufossez
      Institution: University Medical Hospital Freiburg (DE)

15.  Crosstalk between lymphatic endothelial cells in lymphoid organs
      Supervisor: Dr. Christopher Mueller
      PhD Fellow: Shadrack Owusu
      Institution: University of Strasbourg (FR)

16. Investigating the presence and role of MR1-restricted T cells in Inflammatory Bowel Disease (IBD)
      Supervisor: Prof. Dr. Petr Hruz
      PhD Fellow: Vanshika Rastogi
      Institution : University of Basel (CH)

17. The physiology of MR1T cells in tumors and their use in cell therapy
      Supervisor: Prof. Dr. Gennaro De Libero
      PhD Fellow: Natalie Kehrer
      Institution: University of Basel (CH)

 

Research area: Immune-related Diseases
 

18. Functional analysis of genetic variants in patients with inborn errors in T cells or B cells: monogenetic defects in transcription factors in late-onset hypogammaglobulinemia
      Supervisor: Prof. Dr. Bodo Grimbacher
      PhD Fellow: Aishwarya Saxena
      Institution: University Medical Center Freiburg (DE)

19. Modified TCRs on human T cells targeting tumor cells
      Supervisor: Prof. Dr. Wolfgang Schamel
      PhD Fellow: Trang Nguyen
      Institution: University of Freiburg (DE)

20. Deciphering resistance mechanisms in cancer immunotherapy
      Supervisor: Prof. Dr. Alfred Zippelius
      PhD Fellow: Irene Fusi
      Institution: University of Basel (CH)

21. Contribution of CD44 expressed on tumour-associated macrophages (TAMs) to progression of pancreatic cancer
      Supervisor:  Prof. Dr. Véronique Orian-Rousseau
      PhD Fellow: Nagwa Ibrahim
      Institution: Karlsruhe Institute of Technology (DE)

22. Identification of novel therapeutic targets in oncogenic signaling pathways in mastocytosis
      Supervisor: Prof. Dr. Karin Hartmann
      PhD Fellow: Alina Makeeva
      Institution: University of Basel (CH)

23. Lymphoid stromal cells in common variable immunodeficiency : potential orchestrators of the altered humoral response?
      Supervisor: Prof. Dr. Klaus Warnatz
      PhD Fellow: Victoria Cousin
      Institution: University Medical Center Freiburg (DE)

24. B cell heterogeneity during tuberculosis infection
      Supervisor: Prof. Dr. Carolyn King
      PhD Fellow: Wadschma Naderi
      Institution: University of Basel (CH)

25. Determining the prevalence of binding epitopes for autoantibodies in the human population
      Supervisor: Prof. Dr. Frank Breitling
      PhD Fellow: Karen Cárdenas Casillas
      Institution: Karlsruhe Institute of Technology (DE)

26. Heterogeneity of virus specific CD8+ T cell dysfunction in HIV infection
      Supervisor: Prof. Dr. Robert Thimme
      PhD Fellow: Wasihun Hailemichael
      Institution: University Medical Center Freiburg (DE)

27. Structural and functional characterization of human cytomegalovirus (HCMV) Fcγ binding glycoprotein interaction with B cells
      Supervisor: Prof. Dr. Hartmut Hengel
      PhD Fellow: Haneen Daralnakhla
      Institution: University Medical Center Freiburg (DE)

 

The EURIdoc programme receives funding from the European Union's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant 101034170.