Our Research Projects
Research area: Hematopoiesis and Development
1. Function of endothelial cells or mesenchymal cells in hematopoiesis
Supervisor: Dr. Nathalie Brouard/Dr. Catherine Léon
PhD Fellow:
Institution: University of Strasbourg (FR)
2. Role of Ikaros in the development of Th17 lymphocytes
Supervisor: Dr. Susan Chan/Dr. Céline Charvet
PhD Fellow: Caroline Targino
Institution: University of Strasbourg (FR)
3. Stroma – plasma cell interaction as driver of antibody-mediated autoimmune disease
Supervisor: Prof. Dr. Reinhard Voll
PhD Fellow: Paola Fernanda Ruiz Aparicio
Institution: University Medical Center Freiburg (DE)
4. Drug targeting mesenchymal - hematopoietic cell interactions
Supervisor: Dr. Christopher Mueller
PhD Fellow: Guillermo Federico Perez
Institution: University of Strasbourg (FR)
5. Targeting drivers of disease progression in hemophagocytic lymphohistiocytosis (HLH)
Supervisor: Prof. Dr. Stephan Ehl
PhD Fellow:
Institution: University Medical Center Freiburg (DE)
6. 3D model of olfactory mucosa immune defense against SARS-Cov2 infection
Supervisor: Dr. Vincent Flacher
PhD Fellow: Annia Pérez Riverón
Institution: University of Srasbourg (FR)
7. Investigating macrophage populations regarding cytomegalovirus infection
Supervisor: Prof. Dr. Philipp Henneke
PhD Fellow: Agnibesh Dey
Institution: University Medical Center Freiburg (DE)
8. Edification of the blood system in the human embryo: toward de novo generation of Hematopoietic Stem Cells
Supervisor: Dr. Manuela Tavian
PhD Fellow: Mahassen El Khoury
Institution: University of Strasbourg (FR)
Research area: Innate and Adaptive Effector Functions
9. Regulation of the immune response by the spleen
Supervisor: Dr. Blandine Maitre
PhD Fellow: Gabriel Rojas Jiménez
Institution: University of Strasbourg (FR)
10. Post translational modifications of IL-1β; regulation and roles in IL-1β activation
Supervisor: Prof. Dr. Georg Häcker
PhD Fellow: Danielle Paige Anthony
Institution: University Medical Center Freiburg (DE)
11. Modulating T cell signaling for improved anti-tumor responses
Supervisor: Prof. Dr. Björn Lillemeier
PhD Fellow: Vasileios Morfos
Institution: University of Freiburg (DE)
12. Dysregulation of B cell function in ANCA associated vasculitis
Supervisor: Prof. Dr. Marta Rizzi
PhD Fellow: Bruno Benassini
Institution: University Medical Center Freiburg (DE)
13. Characterizing the role of exhausted T cells in hepatocellular carcinoma
Supervisor: Prof. Dr. Bertram Bengsch
PhD Fellow: Andreea Mesesan
Institution: University Medical Hospital Freiburg (DE)
14. Subversion of B cell affinity maturation in chronic viral infection
Supervisor: Prof. Dr. Daniel Pinschewer
PhD Fellow: Cemre Seven
Institution: University of Basel (CH)
15. Impact of macrophages signaling and metabolism on NLRP3 inflammasome activity
Supervisor: Prof. Dr. Olaf Groß
PhD Fellow: Clara Dufossez
Institution: University Medical Hospital Freiburg (DE)
16. Stroma - macrophage cross-talk in lymphoid organ development and homeostasis
Supervisor: Dr. Christopher Mueller
PhD Fellow: Shadrack Owusu
Institution: University of Strasbourg (FR)
17. Mucosal T cell immunity: MR1 restricted T cells in chronic intestinal inflammation
Supervisor: Prof. Dr. Petr Hruz
PhD Fellow: Vanshika Rastogi
Institution : University of Basel (CH)
18. The physiology of MR1T cells in tumors and their use in cell therapy
Supervisor: Prof. Dr. Gennaro De Libero
PhD Fellow: Natalie Kehrer
Institution: University of Basel (CH)
Research area: Immune-related Diseases
19. Functional analysis of genetic variants in patients with inborn errors in T cells or B cells: monogenetic defects in transcription factors in late-onset hypogammaglobulinemia
Supervisor: Prof. Dr. Bodo Grimbacher
PhD Fellow: Aishwarya Saxena
Institution: University Medical Center Freiburg (DE)
20. Modified TCRs on human T cells targeting tumor cells
Supervisor: Prof. Dr. Wolfgang Schamel
PhD Fellow: Trang Nguyen
Institution: University of Freiburg (DE)
21. Deciphering resistance mechanisms in cancer immunotherapy
Supervisor: Prof. Dr. Alfred Zippelius
PhD Fellow: Irene Fusi
Institution: University of Basel (CH)
22. Contribution of CD44 expressed on tumour-associated macrophages (TAMs) to progression of pancreatic cancer
Supervisor: Prof. Dr. Véronique Orian-Rousseau
PhD Fellow: Nagwa Ibrahim
Institution: Karlsruhe Institute of Technology (DE)
23. Identification of novel therapeutic targets in oncogenic signaling pathways in mastocytosis
Supervisor: Prof. Dr. Karin Hartmann
PhD Fellow: Alina Makeeva
Institution: University of Basel (CH)
24. Lymphoid stromal cells in common variable immunodeficiency : potential orchestrators of the altered humoral response?
Supervisor: Prof. Dr. Klaus Warnatz
PhD Fellow: Victoria Cousin
Institution: University Medical Center Freiburg (DE)
25. Pulmonary macrophage heterogeneity and mycobacteria infection
Supervisor: Prof. Dr. Carolyn King
PhD Fellow: Nikos Pantouloufos
Institution: University of Basel (CH)
26. Determining binding epitopes for autoantibodies in lupus (SLE) or in Sjögren syndrome
Supervisor: Prof. Dr. Frank Breitling
PhD Fellow: Karen Cárdenas Casillas
Institution: Karlsruhe Institute of Technology (DE)
27. Heterogeneity of virus specific CD8+ T cell dysfunction in chronic Hepatitis B infection
Supervisor: Prof. Dr. Robert Thimme
PhD Fellow: Wasihun Hailemichael
Institution: University Medical Center Freiburg (DE)
28. Structural and functional characterization of human cytomegalovirus (HCMV) Fcγ binding glycoprotein interaction with B cells
Supervisor: Prof. Dr. Hartmut Hengel
PhD Fellow: Haneen Daralnakhla
Institution: University Medical Center Freiburg (DE)