| | PhD project | Supervisor | City |
| | Research area: Hematopoiesis and development | | |
| 1 | A) Stiffness sensing of bone marrow endothelial cell or
B) Matrix stiffness sensing and proplatelet formation | Nathalie Brouard / Catherine Léon | Strasbourg |
| 2 | A) Role of Ikaros in Th17 cell development or
B) Role of Ikaros in the regulation of T-cell pathogenicity | Susan Chan /
Céline Charvet | Strasbourg |
| 3 | A) Stroma-plasma cell interaction as driver of autoimmune disease or
B) Mesenchymal cell specialization and B lymphocyte differentiation | Reinhard Voll | Freiburg |
| 4 | A) B cell differentiation by stroma and macrophages in autoimmunity or
B) B cell survival and transformation by stroma in lymphoma | Christopher Mueller | Strasbourg |
| 5 | A) STAT3 at the crossroads between cancer and autoimmunity or
B) Immunopathology in acute versus chronic HLH | Stephan Ehl | Freiburg |
| 6 | A) Immune defense of the human olfactory mucosa against viral infections or
B) Autophagy for nonpeptidic antigen presentation by skin DCs | Vincent Flacher | Strasbourg |
| 7 | A) Macrophage adaptation to barrier tissue niches in chronic infection or
B) Differentiation of nerve-and vessel-associated tissue macrophages | Philipp Henneke | Freiburg |
| 8 | A) Identificationof genes implied in hematopoietic specification
B) Characterizationof hemogenic endothelium | Manuela Tavian | Strasbourg |
| | Research area: Innate and adaptive effector functions | | |
| 9 | A) Cellular mechanisms of platelet allo-immunization or
B) Regulation of the immune response by the spleen | Blandine Maitre | Strasbourg |
| 10 | A) Regulation of inflammasomes by post-translational modifications. or
B) RIP kinase regulated metabolism and its impact on inflammation>. | Georg Häcker | Freiburg |
| 11 | A) Single molecule microscopy analyses of signaling mechanisms in T cells or
B) Modulating T cell signaling for improved anti-tumor responses | Björn Lillemeier | Freiburg |
| 12 | A) Extrafollicular responses in autoantibody-mediated autoimmune diseases or
B) Break of tolerance in the B cell compartment: generation and maintenance of self-antigen specific memory B cells | Marta Rizzi | Freiburg |
| 13 | A) Profiling the cellular metabolic landscape of human T cell differentiation in chronic infection and cancer or
B) Role of cellular stress pathways in exhausted T cells | Bertram Bengsch | Freiburg |
| 14 | A) Affinity maturation in chronic viral infection or
B) Clonal competition of B cells in chronic viral infection | Daniel Pinschewer | Basel |
| 15 | A) Molecular signals triggering inflammasome activation or
B) Macrophage-specific pro-inflammatory cell death mechanisms | Olaf Groß | Freiburg |
| 16 | A) Macrophage heterogeneity and B cell activation or
B) Stroma - macrophage cross-talk in lymphoid organ development and homeostasis | Christopher Mueller | Strasbourg |
| 17 | A) TCR γδ cells in Inflammatory Bowel Disease or
B) MR-1 restricted T cells in chronic intestinal inflammation | Petr Hruz | Basel |
| 18 | A) The physiology of MR1T cells and their role in autoimmune diseases or
B) MR1T cells in cell therapy of tumors | Gennaro De Libero | Basel |
| | Research area: Immune-related diseases | | |
| 19 | A) Genetic engineering of bacteria to combat inflammatory bowel disease or
B) Underlying mechanisms in in immunodeficiency and immune dysregulation of syndroms due to actin cytoskeleton abnormalities or
C) Development of the genetic immunology advisor platform: Gemma-P | Bodo Grimbacher | Freiburg |
| 20 | A) Modified TCRs on human T cells targeting tumor cells or
B) Chimeric antigen receptors to fight against SARS-CoV-2 | Wolfgang Schamel | Freiburg |
| 21 | A) Dissecting immune synapse polariziation in exhausted T cells or
B) Deciphering metabolic pathways in exhausted T cells | Alfred Zippelius | Basel |
| 22 | A) Contribution of CD44 expressed on tumour associated macrophages, to progression of pancreatic cancer or
B) The CD44/CXCR4 interplay in immune suppression of pancreatic cancer | Véronique Orian-Rousseau | Karlsruhe |
| 23 | A) Understanding microRNA biology to improve T cell therapy or
B) Exploiting microRNAs for CAR T design | Lukas Jeker | Basel |
| 24 | A) The stroma niche of disturbed germinal center or
B) Extrafollicular plasma cell responses in patients with primary immunodeficiency | Klaus Warnatz | Freiburg |
| 25 | A) Pulmonary macrophage heterogeneity and mycobacteria infection or
B) Functional impact of antibodies during mycobacteria infection | Carolyn King | Basel |
| 26 | A) Determining binding epitopes for autoantibodies in lupus or
B) Determining binding epitopes for autoantibodies in Sjögren’s syndrome | Frank Breitling | Karlsruhe |
| 27 | A) Disease-specific heterogeneity of exhausted T cells or
B) Impact of co-infection on T cell exhaustion | Robert Thimme | Freiburg |
| 28 | A) Modulation of B cell activation by cytomegalovirus or
B) Modulation of B cell activation in COVID-19 | Hartmut Hengel | Freiburg |
