Upper Rhine
Immunology Group

EURIdoc PhD Projects

 

PhD project

Supervisor

City

 

Research area: Hematopoiesis and development

 

 

1        

A) Stiffness sensing of bone marrow endothelial cell or
B) Matrix stiffness sensing and proplatelet formation

Nathalie Brouard /   Catherine Léon

Strasbourg
2

A) Role of Ikaros in Th17 cell development or
B) Role of Ikaros in the regulation of T-cell pathogenicity

Susan Chan /
Céline Charvet

Strasbourg
3

A) Stroma-plasma cell interaction as driver of autoimmune disease or
B) Mesenchymal cell specialization and B lymphocyte differentiation

Reinhard Voll

Freiburg
4

A) B cell differentiation by stroma and macrophages in autoimmunity or
B) B cell survival and transformation by stroma in lymphoma

Christopher Mueller

Strasbourg
5

A) STAT3 at the crossroads between cancer and autoimmunity or
B) Immunopathology in acute versus chronic HLH

Stephan Ehl

Freiburg
6

A) Immune defense of the human olfactory mucosa against viral infections or
B) Autophagy for nonpeptidic antigen presentation by skin DCs

Vincent Flacher

Strasbourg

7

A) Macrophage adaptation to barrier tissue niches in chronic infection or
B) Differentiation of nerve-and vessel-associated tissue macrophages

Philipp Henneke

Freiburg
8

A) Identificationof genes implied in hematopoietic specification
B) Characterizationof hemogenic endothelium

Manuela Tavian

Strasbourg

 

Research area: Innate and adaptive effector functions

 

 

9

A) Cellular mechanisms of platelet allo-immunization or
B) Regulation of the immune response by the spleen

Blandine Maitre

Strasbourg
10

A) Regulation of inflammasomes by post-translational modifications. or
B) RIP kinase regulated metabolism and its impact on inflammation
>.

Georg Häcker

Freiburg
11

A) Single molecule microscopy analyses of signaling mechanisms in T cells or
B) Modulating T cell signaling for improved anti-tumor responses

Björn Lillemeier

Freiburg

12

A) Extrafollicular responses in autoantibody-mediated autoimmune diseases or
B) Break of tolerance in the B cell compartment: generation and maintenance of self-antigen specific memory B cells

Marta Rizzi

Freiburg

13

A) Profiling the cellular metabolic landscape of human T cell differentiation in chronic infection and cancer or
B) Role of cellular stress pathways in exhausted T cells

Bertram Bengsch

Freiburg

14

A) Affinity maturation in chronic viral infection or
B) Clonal competition of B cells in chronic viral infection

Daniel Pinschewer

Basel
15

A) Molecular signals triggering inflammasome activation or
B) Macrophage-specific pro-inflammatory cell death mechanisms

Olaf Groß

Freiburg

16

A) Macrophage heterogeneity and B cell activation or
B) Stroma - macrophage cross-talk in lymphoid organ development and homeostasis

Christopher Mueller

Strasbourg

17

A) TCR γδ cells in Inflammatory Bowel Disease or
B) MR-1 restricted T cells in chronic intestinal inflammation

Petr Hruz

Basel

18

A) The physiology of MR1T cells and their role in autoimmune diseases or
B) MR1T cells in cell therapy of tumors

Gennaro De Libero

Basel

 

Research area: Immune-related diseases

 

 

19

A) Genetic engineering of bacteria to combat inflammatory bowel disease or
B) Underlying mechanisms in in immunodeficiency and immune dysregulation of syndroms due to actin cytoskeleton abnormalities or
C) Development of the genetic immunology advisor platform: Gemma-P

Bodo Grimbacher

Freiburg

20

A) Modified TCRs on human T cells targeting tumor cells or
B) Chimeric antigen receptors to fight against SARS-CoV-2

Wolfgang Schamel

Freiburg

21

A) Dissecting immune synapse polariziation in exhausted T cells or
B) Deciphering metabolic pathways in exhausted T cells

Alfred Zippelius

Basel

22

A) Contribution of CD44 expressed on tumour associated macrophages, to progression of pancreatic cancer or
B) The CD44/CXCR4 interplay in immune suppression of pancreatic cancer

Véronique Orian-Rousseau

Karlsruhe

23

A) Understanding microRNA biology to improve T cell therapy or
B) Exploiting microRNAs for CAR T design

Lukas Jeker

Basel

24

A) The stroma niche of disturbed germinal center or
B) Extrafollicular plasma cell responses in patients with primary immunodeficiency

Klaus Warnatz

Freiburg

25

A) Pulmonary macrophage heterogeneity and mycobacteria infection or
B) Functional impact of antibodies during mycobacteria infection

Carolyn King

Basel

26

A) Determining binding epitopes for autoantibodies in lupus or
B) Determining binding epitopes for autoantibodies in Sjögren’s syndrome

Frank Breitling

Karlsruhe
27

A) Disease-specific heterogeneity of exhausted T cells or
B) Impact of co-infection on T cell exhaustion

Robert Thimme

Freiburg
28

A) Modulation of B cell activation by cytomegalovirus or
B) Modulation of B cell activation in COVID-19

Hartmut Hengel

Freiburg