Upper Rhine
Immunology Group

EURIdoc PhD Projects

Research area: Hematopoiesis and Development

1.  Function of endothelial cells or mesenchymal cells in hematopoiesis
     Supervisor:  Dr. Nathalie Brouard/Dr. Catherine Léon
     PhD Fellow:
     Institution: University of Strasbourg (FR) 

2. Role of Ikaros in the development of Th17 lymphocytes
     Supervisor:  Dr. Susan Chan/Dr. Céline Charvet
     PhD Fellow: Caroline Targino
     Institution: University of Strasbourg (FR)

3.  Stroma – plasma cell interaction as driver of antibody-mediated autoimmune disease
     Supervisor: Prof. Dr. Reinhard Voll
     PhD Fellow: Paola Fernanda Ruiz Aparicio
     Institution: University Medical Center Freiburg (DE)

4.   Drug targeting mesenchymal - hematopoietic cell interactions
      Supervisor: Dr. Christopher Mueller
      PhD Fellow: Guillermo Federico Perez
      Institution: University of Strasbourg (FR)

5.  Targeting drivers of disease progression in hemophagocytic lymphohistiocytosis (HLH)
     Supervisor: Prof. Dr. Stephan Ehl
     PhD Fellow:
     Institution: University Medical Center Freiburg (DE)

6. 3D model of olfactory mucosa immune defense against SARS-Cov2 infection
     Supervisor: Dr. Vincent Flacher
     PhD Fellow: Annia Pérez Riverón
     Institution: University of Srasbourg (FR)

7.  Investigating macrophage populations regarding cytomegalovirus infection
     Supervisor: Prof. Dr. Philipp Henneke
     PhD Fellow: Agnibesh Dey
     Institution: University Medical Center Freiburg (DE)

8.  Edification of the blood system in the human embryo: toward de novo generation of  Hematopoietic Stem Cells
     Supervisor: Dr. Manuela Tavian
     PhD Fellow: Mahassen El Khoury
     Institution: University of Strasbourg (FR)

 

Research area: Innate and Adaptive Effector Functions

9.   Regulation of the immune response by the spleen
      Supervisor: Dr. Blandine Maitre
      PhD Fellow: Gabriel Rojas Jiménez
      Institution: University of Strasbourg (FR) 

10. Post translational modifications of IL-1β; regulation and roles in IL-1β activation
       Supervisor:  Prof. Dr. Georg Häcker
       PhD Fellow: Danielle Paige Anthony
       Institution: University Medical Center Freiburg (DE)

11. Modulating T cell signaling for improved anti-tumor responses
       Supervisor: Prof. Dr.  Björn Lillemeier
       PhD Fellow: Vasileios Morfos
       Institution: University of Freiburg (DE)

12. Dysregulation of B cell function in ANCA associated vasculitis
        Supervisor:  Prof. Dr. Marta Rizzi
        PhD Fellow: Bruno Benassini
        Institution: University Medical Center Freiburg (DE)

13. Characterizing the role of exhausted T cells in hepatocellular carcinoma
       Supervisor: Prof. Dr. Bertram Bengsch
       PhD Fellow: Andreea Mesesan
       Institution: University Medical Hospital Freiburg (DE)

14. Subversion of B cell affinity maturation in chronic viral infection
       Supervisor: Prof. Dr. Daniel Pinschewer
       PhD Fellow: Cemre Seven
       Institution: University of Basel (CH)

15. Impact of macrophages signaling and metabolism on NLRP3 inflammasome activity
       Supervisor: Prof. Dr. Olaf Groß
       PhD Fellow: Clara Dufossez
       Institution: University Medical Hospital Freiburg (DE)

16. Stroma - macrophage cross-talk in lymphoid organ development and homeostasis
       Supervisor: Dr. Christopher Mueller
       PhD Fellow: Shadrack Owusu
       Institution: University of Strasbourg (FR)

17. Mucosal T cell immunity: MR1 restricted T cells in chronic intestinal inflammation
       Supervisor: Prof. Dr. Petr Hruz
       PhD Fellow: Vanshika Rastogi
       Institution : University of Basel (CH)

18. The physiology of MR1T cells in tumors and their use in cell therapy
       Supervisor: Prof. Dr. Gennaro De Libero
       PhD Fellow: Natalie Kehrer
       Institution: University of Basel (CH)

 

Research area: Immune-related Diseases

19. Functional analysis of genetic variants in patients with inborn errors in T cells or B cells: monogenetic defects in transcription factors in late-onset hypogammaglobulinemia
       Supervisor: Prof. Dr. Bodo Grimbacher
       PhD Fellow: Aishwarya Saxena
       Institution: University Medical Center Freiburg (DE)

20. Modified TCRs on human T cells targeting tumor cells
       Supervisor: Prof. Dr. Wolfgang Schamel
       PhD Fellow: Trang Nguyen
       Institution: University of Freiburg (DE)

21. Deciphering resistance mechanisms in cancer immunotherapy
       Supervisor: Prof. Dr. Alfred Zippelius
       PhD Fellow: Irene Fusi
       Institution: University of Basel (CH)

22. Contribution of CD44 expressed on tumour-associated macrophages (TAMs) to progression of pancreatic cancer
       Supervisor:  Prof. Dr. Véronique Orian-Rousseau
       PhD Fellow: Nagwa Ibrahim
       Institution: Karlsruhe Institute of Technology (DE)

23. Identification of novel therapeutic targets in oncogenic signaling pathways in mastocytosis
       Supervisor: Prof. Dr. Karin Hartmann
       PhD Fellow: Alina Makeeva
       Institution: University of Basel (CH)

24. Lymphoid stromal cells in common variable immunodeficiency : potential orchestrators of the altered humoral response?
       Supervisor: Prof. Dr. Klaus Warnatz
       PhD Fellow: Victoria Cousin
       Institution: University Medical Center Freiburg (DE)

25. Pulmonary macrophage heterogeneity and mycobacteria infection
       Supervisor: Prof. Dr. Carolyn King
       PhD Fellow: Nikos Pantouloufos
       Institution: University of Basel (CH)

26. Determining binding epitopes for autoantibodies in lupus (SLE) or in Sjögren syndrome
       Supervisor: Prof. Dr. Frank Breitling
       PhD Fellow: Karen Cárdenas Casillas
       Institution: Karlsruhe Institute of Technology (DE)

27. Heterogeneity of virus specific CD8+ T cell dysfunction in chronic Hepatitis B infection
       Supervisor: Prof. Dr. Robert Thimme
       PhD Fellow: Wasihun Hailemichael
       Institution: University Medical Center Freiburg (DE)

28. Structural and functional characterization of human cytomegalovirus (HCMV) Fcγ binding glycoprotein interaction with B cells
       Supervisor: Prof. Dr. Hartmut Hengel
       PhD Fellow: Haneen Daralnakhla
       Institution: University Medical Center Freiburg (DE)