PhD Fellows


Bruno Benassini

University Medical Center Freiburg, Rheumatology and Clinical Immunology

Project: Dysregulation of B cell function in ANCA associated vasculitis

 

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Our group is interested in the mechanisms of platelet formation in physiopathology and focused on the role of the mechanical microenvironment. Platelets are produced in the bone marrow by megakaryocytes (MKs). The last steps of MK differentiation and platelet release occur when MKs are in contact with endothelial cells (EC) constituting the sinusoid vessels. We recently observed that human ECs from marrow vessels are capable to promote the formation of platelets more efficiently than ECs from other vascular territories. Modifications of mechanical properties of the marrow occur in myeloproliferative neoplasms that usually leads to myelofibrosis, pathological conditions associated with excessive matrix protein deposition around sinusoid vessels and abnormal platelet production.

 

Supervisor: Dr. Nathalie Brouard & Dr. Catherine Léon

Co-supervisor: Dr. Remi Peyronnet (University of Freiburg)


Karen Cárdenas Casillas

Karlsruhe Institute of Technology, Institute of Microstructure Technology

Project: Determining the prevalence of binding epitopes in the human population

 

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Victoria Cousin

University Medical Center Freiburg, CCI - ZTZ

Project: Lymphoid stromal cells in common variable immunodeficiency: potential orchestrators of the altered humoral response?

 

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Haneen Daralnakhla

University Medical Center Freiburg, Institute of Virology

Project: Structural and functional characterization of human cytomegalovrius (HCMV) Fcy binding glycoprotein interaction with B cells

 

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Agnibesh Dey

University Medical Center Freiburg, Institute for Immunodeficiency, CCI

Project: Investigating macrophage populations regarding cytemegovirus infection

 

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Clara Dufossez

University Medical Center Freiburg, Institute of Neuropathology

Project: Impact of macrophages signaling and metabolism on NLRP3 inflammasome activity

 

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Mahassen El Khoury

University of Strasbourg, IGBMC

Project: Role of the Ikaros family proteins in embryonic blood cell development

 

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Irene Fusi

University of Basel, Tumour Immunology

Project: Deciphering resistance mechanisms in cancer immunotherapy

 

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Wasihun Hailemichael

University Medical Center Freiburg, Internal Medicine II

Project: Heterogeneity of virus specific CD8+T cell dysfunction in HIV infection

 

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Nagwa Ibrahim

Karlsruhe Institute of Technology, IBCS-FMS

Project: Contribution of CD44 Expressed on Tumor-Associated Macrophages (TAMs) to Progression of Pancreatic Cancer

 

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Natalie Kehrer

University of Basel

Project: The physiology of MR1T cells in tumors and their use in cell therapy

 

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Alina Makeeva

University of Basel, Allergy & Immunity

Project: Identification of novel therapeutic targets in oncogenic signaling pathways in mastocytosis

 

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Vasileios Morfos

University of Freiburg, Institute of Biology III

Project: Modulating T cell signaling to improve anti-tutor responses

 

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Trang Nguyen

University of Freiburg, Department of Immunology

Project: Modified TCRs on human T cells targeting tumor cells

 

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Shadrack Owusu

University of Strasbourg, Institue of Molecular and Cell Biology

Project: Stroma - macrophage cross-talk in lymphoid organ development and homeostasis

 

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Wadschma Naderi

University of Basel, Department of Biomedicine

Project: Pulmonary macrophage heterogeity and mycobacteria infection

 

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Guillermo Federico Perez

University of Strasbourg, Institute of Molecular and Cell Biology

Project: Drug-targeting of mesenchymal-hematopoietic cell interaction

 

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Annia Pérez Riverón

University of Strasbourg, Institute of Molecular and Cell Biology

Project: 3D model of olfactory mucosa immune defense against SARS-CoV-2 infection

 

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Vanshika Rastogi

University of Basel, Clarunis - Universitäres Bauchzentrum Basel

Project: Investigating the presence and role of MR1-restricted T cells in Inflammatory Bowel Disease (IBD)

 

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Gabriel Rojas Jiménez

University of Strasbourg, EFS Grand Est

Project: Regulation of the immune response by the spleen

 

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Paola Fernanda Ruiz Aparicio

University Medical Center Freiburg, Department of Rheumatology and Clinical Immunology

Project: Stroma - plasma cell interaction as driver of antibody-mediated autoimmune disease

 

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Aishwarya Saxena

University Medical Center Freiburg, Center for Chronic Immunodeficiency

Project: Functional analysis of genetic variants in patients with inborn errors in T cells or B cells: monogenetic defects in transcription factors in late-onset hypogammaglobulinemia

 

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Cemre Seven

University of Basel, Department of Biomedicine

Project: Subversion of B cell affinity maturation in chronic viral infection

 

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Caroline Targino

University of Strasbourg, IGBMC

Project: Role of Ikaros in the development of Th17 lymphocytes

 

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Faten Tlili

University of Strasbourg, EFS Grand Est, Inserm UMRS-1255

Project: Mechanobiology of the blood - bone marrow barrier and impact on platelet formation

 

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Xipeng Wang

University Medical Center Freiburg, Institute of Neuropathology

Project: NLRP proteins in health and disease

 

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